The Human Upgrade: Biohacking for Longevity & Performance
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Episodes
The Truth About Vitamins, Supplements & Prescription Drugs | Phil Cowley : 1567
Pharmacist Phil Cowley discusses the evolution of pharmacy, the impact of PBMs on independent businesses, and the importance of compounding for personalized care.
I Tried EVERY Controversial Focus Drug : 1566
This episode explores the history and science of controversial focus compounds, contrasting banned substances like amphetamines and psychedelics with legal options such as modafinil and racetams.
Placebo Pills, Cannabis, Wall Squats for Blood Pressure, Birdwatching, and the Porn brain : 1564
Dave Asprey discusses recent studies on the efficacy of openly labeled placebos for IBS and the blood pressure benefits of isometric wall squats.
The No-Brainer Solution To Stop Overeating : 1565
Host Dave Asprey interviews Sarah Kennedy, founder of Calicurb, to explore the science of hunger and a hops-based supplement that mimics GLP-1 effects.
The Easiest Treatment That Made Me 15 Years Younger : 1563
Dave Asprey and Dr.
How To Reverse Your Age For $5 Day (Budget Biohacking) : 1562
Dave Asprey outlines an affordable, evidence-based longevity protocol costing just $5 a day, featuring supplements like omega-3s, Glynac, and…
Avoid THESE "Healthy" Superfoods : 1561
Dave Asprey and Terry Cochran discuss the metabolic impacts of modern food systems, focusing on how industrial farming and glyphosate disrupt protein, sulfur, and oxalate metabolism.
How to Trigger Flow States From The 5 Brain Chemicals You Need : 1559
Dave Asprey and Steven Kotler explore the neuroscience of flow states, identifying caffeine as a key "flow hack" while discussing the neurochemical cocktail that drives peak performance.
The 6-Minute Morning Routine That Can Change Your Life : 1558
Dave Asprey and Hal Elrod discuss the science and practice of the "Miracle Morning" and SAVERS routine, emphasizing that morning rituals should align…
400mg Before Bed Improves Deep Sleep by 1700% : 1557
Dave Asprey explains how to restore deep sleep using a stack of interventions, starting with 400mg of apigenin to gently activate GABA receptors without sedation.
John Gray: Why Men Stop Wanting Their Wives : 1556
Dave Asprey interviews John Gray, author of "Men Are From Mars, Women Are From Venus," to explore how modern gender dynamics and hormonal biology impact relationships.
Sleep Expert: 80% of Sleep Problems Come From THIS : 1555
Dave Asprey interviews clinical psychologist Dr.
The Science Behind Joint and Cartilidge Repair : 1554
Dave Asprey and Kieran Kennedy discuss how vascular dysfunction drives joint degeneration and muscle loss.
Your Brain Has a Focus Switch (Here's How to Turn It On) : 1553
Dave Asprey explains that focus is a chemical state driven by norepinephrine and dopamine, which are depleted by chronic stress, poor sleep, and sedentary habits.
Infections & Cancer, Finasteride Side Effects, Blueberry Benefits, Vitamin D & Fertility, and CoQ10 : 1552
Dave Asprey explores how chronic infections like H.
How to Unlock Psychic Abilities to Know When You’ll Die : 1551
Dave Asprey discusses the scientific basis of consciousness with professional psychic and medical device inventor Julie Ryan.
How to Live Healthier Without Obsessing Over Health : 1550
Cora Organic founder shares how her mother’s cancer diagnosis inspired her to create a certified organic skincare brand, emphasizing that skin absorbs what we apply.
It's Boring, But It Slashed ALL My Visceral Fat In My 50s : 1549
Dave Asprey shares his journey from being 300 pounds to peak health by debunking conventional diet advice.
Vagus Nerve Memory, Cat Cancer Genes, Inherited Intelligence, Mulberry Microbes, and Vitamin D : 1548
Dave Asprey covers recent biohacking research, including a trial showing ear-based vagus nerve stimulation may improve memory in mild cognitive impairment.
Dave’s Anti-Aging Skincare Routine: Exosomes, Methylene Blue & NAD+ : 1547
Dave Asbury interviews Young Goose co-founders Amate and Anastasia on longevity-focused skincare, emphasizing that wrinkles are symptoms of underlying cellular decline.
The Silent Fatty Liver Epidemic: Why Thin, Sober People Are Still at Risk : 1546
Host Dave Asprey and Sigi Clavian of Deliverance discuss liver health, explaining that 100 million Americans have undiagnosed fatty liver disease due to poor blood panel detection.
Every Way to Melt Visceral Fat FAST In 14 Minutes : 1545
Host Dave Asprey outlines six simple, affordable biohacking methods to reduce visceral fat, prioritizing stress reduction to lower cortisol.
Ozempic Hair, GLP-1 Kids, Gut-Brain Anxiety, Food Additives, Taurine, and more : 1544
Dave Asprey explores Novo Nordisk’s potential entry into hair loss treatments and the rapid evolution of follicle-reactivating drugs.
The Best Singular Hack To Change EVERYTHING About Your Life : 1543
Dr.
15g Every Morning for Anti-Aging Mitochondria : 1541
Dave Asbury interviews Catherine, a 70-year-old algae expert and founder of Energy Bits, to discuss the longevity benefits of microalgae.
I Wasted 10 Years Stuck With Brain Fog Until I Learned This : 1540
Host Dave Asprey shares his personal recovery from mold-induced brain damage, explaining how mycotoxins disrupt mitochondria and cause chronic symptoms like fatigue and brain fog.
Teal Swan - Beyond the Veil of Ego, AI & Wisdom : 1539
Dave Asprey interviews Teal Swan, a spiritual practitioner with extrasensory abilities, discussing her unique perception of reality and the nature of ego.
How to Hack Your Smell for Memory and Longevity WHILE YOU SLEEEP! : 1538
Dr.
Josh Duhamel on Nootropics, Peptides, and Testosterone at 53 : 1537
Dave Asprey and actor Josh Jamison discuss biohacking, longevity, and the importance of hormone optimization for men and women.
The Peptide Secrets to a Youthful Face : 1536
Dave Asprey and Carolina Reyes de Oliveira discuss One Skin’s new rich moisturizer, designed to combat age-related dehydration and menopause-related skin thinning.
What 36 Hours Without Sugar Does to Your Body : 1535
This episode details the hour-by-hour physiological changes that occur when you cut sugar for 36 hours, explaining how insulin levels drop to unlock fat storage and reduce inflammation.
New Seafood Superfood, Apple Watch Health Age, Botanical Drugs, Cannabis IQ, and Blueberries : 1534
Dave Asprey covers recent biohacking news, starting with research showing sea squirt plasmalogens reversed aging signs in mice.
Everything You Need To Know About Your Poop | Gut Surgeon Explains : 1533
Dr.
If I Had To Lose 50 Pounds FAST, I’d Do THIS : 1532
Dave Asprey discusses a top weight loss doctor’s three-step protocol for losing 50 pounds by addressing insulin resistance.
Raw Garlic, Egg Yolks, Heat Strokes, and Melatonin : 1531
Dave Asprey analyzes raw garlic’s benefits and cognitive downsides, advocates for HEPA filtration to reduce neuroinflammation, and highlights protective egg yolk peptides.
Jenny McCarthy | The 3 Questions You’re NEVER Supposed to Ask : 1530
Dave Asprey interviews Jenny, a mother who reversed her son’s autism diagnosis through dietary changes and detoxification after a severe reaction to the MMR vaccine.
3 Longevity Drugs I QUIT (And the 4 I Take Instead) : 1529
Dave Asprey critiques popular longevity drugs like metformin, rapamycin, and statins, arguing they blunt regeneration or lack human data.
7 Brain Compounds I Take For Superhuman Focus : 1528
Host Dave Asprey shares seven underrated supplements to boost brain energy and longevity, drawing from his personal biohacking journey.
Change Your Morning, Change Your Life! Hal Elrod : 1527
Dave Asprey interviews Hal Elrod, author of The Miracle Morning, about his updated book and the philosophy behind the morning routine.
Learn THIS And You’ll Become Impossible To Trigger : 1526
Dave Asprey hosts Johnny Miller to discuss nervous system mastery, interoception, and emotional fluidity as critical components of longevity.
Jim Kwik: If You're Using AI Like This, You're Killing Your Brain : 1525
Dave Asprey interviews memory expert Jim Quick about leveraging AI to enhance, rather than replace, human intelligence.
The Most Important Longevity Molecule I've Ever Found : 1524
Dave Asprey explains how declining NAD+ levels drive aging and energy loss, citing Nobel Prize research on its role in cognitive health.
The Scientist Monk: Gurudev Sri Sri Ravi Shankar : 1523
Dave Asprey interviews Gurudev Sri Sri Ravi Shankar live at the Art of Living Center, discussing breathwork, spirituality, and biohacking.
The Wild New Theory of Cancer (It's GOOD For You?) : 1522
Dave Asprey interviews Patrick Coles on his Toxin Sequestration Theory, which posits that chronic diseases and cancer are defense mechanisms against toxic overload rather than genetic failures.
Scream Cream and Weekly Injections (Double Episode) | Gabby Reece : 1521
Dave Asprey discusses biohacking mitochondria to enhance longevity, performance, and spiritual perception, linking quantum biology to reality creation.
It's Weird, But It Turns On Your Anti-Aging Switch : 1520
Dave Asprey explains how modern stress and eating habits suppress mitophagy, the cellular cleanup process essential for longevity.
Depressing Fruit, Vitamin (C)ancer, Sheep Wool, Oral GLP-1s, Endless Exercise, and more : 1519
Dave Asprey reviews biohacking news, including an inhaled Alzheimer’s drug trial, regenerative brain cells, and keratin bone scaffolds.
Dave Solo Pod: The Original Smart Drug Masterclass : 1518
Dave Asprey explores racetams, the original nootropics, detailing their history, mechanisms, and benefits for memory, focus, and neuroprotection.
Steven Greer | UAP’s and Remote Viewing Techniques for Non-Human Life : 1517
Dave Asprey interviews Dr.
300mg Improves Appearance of Wrinkles In 7 Days (Study) : 1516
Dave Asprey explains why glutathione, the "master antioxidant," is crucial for combating oxidative stress and skin aging, rather than just boosting collagen.