3 Longevity Drugs I QUIT (And the 4 I Take Instead) : 1529
Summary
Dave Asprey critiques popular longevity drugs like metformin, rapamycin, and statins, arguing they blunt regeneration or lack human data. He instead recommends low-dose tadalafil for vascular health, SGL2 inhibitors and acarbose for metabolic benefits, and low-dose naltrexone for immune modulation. Asprey emphasizes that these pharmaceuticals should complement, not replace, foundational lifestyle biohacking for optimal longevity.
Topics discussed
Introduction and skepticism on popular longevity drugs
Why Metformin is not recommended for healthy people
Rapamycin: History, mechanisms, and human trial results
Why Statins are poor choices for longevity
Tadalafil (Cialis) for vascular health and brain function
SGL2 Inhibitors: Benefits for heart, kidney, and lifespan
Acarbose: Gut health and mouse longevity studies
Low Dose Naltrexone (LDN) for immunity and inflammation
Dosage recommendations and how to access these drugs
Summary of Yes/No lists and medical disclaimer
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