The Human Upgrade: Biohacking for Longevity & Performance The Human Upgrade: Biohacking for Longevity & Performance

Josh Duhamel on Nootropics, Peptides, and Testosterone at 53 : 1537

Sep 16, 2026 · 55m

Summary

Dave Asprey and actor Josh Jamison discuss biohacking, longevity, and the importance of hormone optimization for men and women. They explore the benefits of testosterone and HRT, debunking myths about side effects and the necessity of medical supervision. The conversation also covers the spiritual and mental health impacts of breathwork and psychedelics, as well as practical parenting tips like natural elimination communication.

Topics discussed

Intro: Feeling stronger and the Human Upgrade Sponsor: Modafinil and Mod Sponsor: Omnibiotic probiotics Guest intro: Josh James and Gatling Health Health shifts in entertainment and diet Food sensitivity, kids, and nutrition choices Alcohol, supplements, and Burning Man Ayahuasca experiences and safety concerns Quantum reality, breathwork, and spiritual connection Spirituality, church, and handling bad trips Online trolls and personal resilience Starting with the body and testosterone branding Sponsor: Timeline mitochondria support Sponsor: Kinetic ketones Testosterone therapy history and benefits Hormone replacement for women and menopause Myths about testosterone and self-regulation Josh's low T story and public perception Gatling Health model and peptide guidance Testosterone dosing, injection vs. cream Life changes, parenting, and baby smell Natural elimination communication and potty training Birth rates, longevity, and having kids at 53 Myths about stopping testosterone Sponsor: iRestore hair and skin Life choices, sacrifice, and family dynamics Sibling age gaps and Fargo vs. Moorhead Sourcing peptides and supply chain security Personal responsibility in healthcare decisions Supplement regulation history and access Cosmetic procedures and GLP-1 caution Low-dose GLP-1 for longevity Synergy of hormones, gym, and spirituality Wasted money on health and stem cells Time perception and friend group dynamics Acting career, stage fright, and memory Nootropics: Aniracetam and Modafinil Cognitive resilience and ADHD/Autism Optimization for longevity and dark forces Call to action: Check testosterone levels Medical disclaimer and podcast ownership
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