The Biblical Anti-Aging Fruit That Scientists Are Obsessed With : 1470
Summary
Dave Asprey interviews Chris Wrench, co-founder of Timeline, about their discovery of Urolithin A, a compound that triggers mitophagy to improve mitochondrial function. They discuss clinical evidence showing Urolithin A extends lifespan in worms, boosts endurance in mice, and reduces wrinkles in humans. The episode covers why direct Urolithin A supplementation outperforms pomegranate extracts and highlights Timeline’s partnership with L'Oreal for topical skincare applications.
Topics discussed
Intro: Calroy Health, Viome, and Biohacking Basics
Timeline History and the Focus on Mitochondria
From Pomegranates to Urolithin A Discovery
Worm Studies and Mitophagy Mechanism
Mitochondrial Biology and Human Clinical Data
Why Pomegranate Extract Isn't Enough
Topical Urolithin A for Skin Health and Wrinkles
Immune System Benefits and XPRIZE HealthSpan
Marketing vs. Science and Global Research Network
IV Delivery and NK Cell Immune Study Results
Affordable Longevity and Study Funding Models
Dosage, Consistency, and Future Testing
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