BDNF Superpowers Through MDMA and Ketamine | Dr. Dave Rabin : 1486
Jun 18, 2026 · 1h 1m
Summary
Dave Asprey interviews Dr. Dave Rabin on using psychedelics and nervous system regulation to treat trauma and mental illness. They discuss how ketamine offers a safe entry point, while MDMA and psilocybin provide profound healing by activating safety responses. The episode highlights the Apollo Neuro wearable for vagus nerve stimulation and critiques modern medicine’s failure to address chronic stress and epigenetic trauma.
Topics discussed
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Sponsor: Viome Personalized Nutrition Testing
Introduction: Dr. Dave Smith and Treatment-Resistant Mental Illness
Psychedelic Safety, Medical Errors, and Historical Parallels
Ketamine as a Safer Alternative to Serotonergic Psychedelics
Sponsors: Element Hydration and Gatlin Optimization
Managing Anxiety and Serotonin Syndrome Risks
The Vagus Nerve, Autonomic Nervous System, and Safety
Experiential Learning and Rewiring Fear Responses
Modern Overstimulation and Chronic Stress States
Neuroelectricity, Trauma, and Epigenetic Changes
Sponsor: OneSkin Anti-Aging Skincare
MDMA-Assisted Therapy and Epigenetic Repair of Trauma
The Role of Therapy, Safety, and Professional Guidelines
FDA Delays, Corporate Interference, and Economic Impact
Personal Ketamine Experience and Critique of Traditional Therapy
Conclusion: Future of Human Potential and Book Promotion
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