Staph Retreat
Mar 20, 2026
Summary
This Radiolab episode explores the discovery of an ancient remedy from Bald’s Leech Book, an 11th-century medical text. Microbiologist Freya Harrison and historian Christina Lee tested a recipe for eye infections, finding it effectively kills MRSA, a drug-resistant superbug. The story highlights the ongoing arms race between antibiotics and bacterial resistance, suggesting that historical medicines may offer new solutions when modern drugs fail.
Topics discussed
Sponsors and intro
Lulu introduces the MRSA story
Alexander Fleming and the discovery of penicillin
The rapid rise of antibiotic resistance
The arms race of drugs vs. superbugs
The decline of new antibiotic development
Part two: Freya Harrison and Christina Lee
A microbiologist and a historian meet
Bald's Leech Book and ancient remedies
The 'Best Medicine' recipe for eye infections
Recreating the ancient potion in the lab
Testing the brew against Staph bacteria
Success against MRSA superbugs
Interpreting historical medical language
Why ancient remedies work today
Modern clinical trials and patent questions
Credits and closing sponsors
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