Radiolab Radiolab

Staph Retreat

Mar 20, 2026

Summary

This Radiolab episode explores the discovery of an ancient remedy from Bald’s Leech Book, an 11th-century medical text. Microbiologist Freya Harrison and historian Christina Lee tested a recipe for eye infections, finding it effectively kills MRSA, a drug-resistant superbug. The story highlights the ongoing arms race between antibiotics and bacterial resistance, suggesting that historical medicines may offer new solutions when modern drugs fail.

Topics discussed

Sponsors and intro Lulu introduces the MRSA story Alexander Fleming and the discovery of penicillin The rapid rise of antibiotic resistance The arms race of drugs vs. superbugs The decline of new antibiotic development Part two: Freya Harrison and Christina Lee A microbiologist and a historian meet Bald's Leech Book and ancient remedies The 'Best Medicine' recipe for eye infections Recreating the ancient potion in the lab Testing the brew against Staph bacteria Success against MRSA superbugs Interpreting historical medical language Why ancient remedies work today Modern clinical trials and patent questions Credits and closing sponsors
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