Radiolab Radiolab

Antibiotic Apocalypse

Mar 27, 2026

Summary

In this live episode, host Soren Wheeler and ER doctor Avir Mitra explore the crisis of antibiotic resistance. Mitra illustrates how bacteria rapidly evolve and share resistance genes, contrasting human limitations with bacterial adaptability. The discussion highlights the massive role of agricultural antibiotic use, featuring Purdue Chicken’s efforts to eliminate them. Finally, the episode touches on the urgent need for new medical strategies to combat these superbugs.

Topics discussed

Intro and Welcome to Live Radiolab Dr. Avir Mitra's Background and the Rise of Superbugs The '100-Year Bubble' of Antibiotic Safety Stephanie's Husband Tom's Critical Illness Horizontal Gene Transfer and Bacterial Evolution Demo The Economic Crisis in Antibiotic Development Commercial Break Antibiotics in Agriculture and Chicken Farming Bruce Stewart-Brown on Reforming Chicken Farming Tom's Coma and the Decision to Fight Commercial Break Phage Therapy: Using Viruses to Kill Bacteria Tom's Recovery and Hope for the Future Tom's Perspective from the Coma Credits and Closing Remarks
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