Return of Alpha Gal
Summary
This Radiolab episode explores alpha-gal syndrome, a rare red meat allergy triggered by Lone Star tick bites. Host Robert Krulwich and producer Amy Pearl investigate how tick saliva causes the immune system to attack a sugar found in mammalian meat. The story concludes with a 2021 update on genetically modified "GalSafe" pigs, whose organs and meat lack the offending sugar, potentially offering hope for patients like Pearl.
Topics discussed
Sponsors and Radiolab intro
Amy's sudden meat allergy story
The science of Alpha-gal and tick bites
Tick biology and Amy's life with the allergy
Genetically modified pigs for transplants
Amy's reaction to the GM pig news
Update on patient Rick Slayman and credits
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