Peptides Explained Peptides Explained

The 11 Peptides I Find Most Compelling

Jul 29, 2026 · 45m

Summary

Host John Garrett reviews his top 11 peptides, categorizing them by evidence level from FDA-approved drugs like terzepatide to experimental compounds like BPC-157. He discusses metabolic agents, growth hormone secretagogues, and repair peptides, sharing personal usage experiences and clinical data. The episode emphasizes distinguishing between robust human trials and anecdotal reports while warning against bro science.

Topics discussed

Sponsors and episode introduction Disclaimer and evidence rating system explanation Overview of top 11 peptides and selection criteria Terzepatide: Mechanism, efficacy, and side effects Retatrutide: Triple agonist potential and risks Tesamorelin: Visceral fat reduction and GH signaling Ipamorelin: Selective GH secretagogue benefits BPC-157: Healing properties and regulatory status TB-500: Thymosin beta-4 and wound healing GHK-Copper: Skin health and topical vs systemic use KPV: Anti-inflammatory peptide for gut and skin PT-141: FDA-approved treatment for sexual desire MOTS-c and SS-31: Mitochondrial function peptides Summary of user reports and final conclusions
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