The 11 Peptides I Find Most Compelling
Jul 29, 2026 · 45m
Summary
Host John Garrett reviews his top 11 peptides, categorizing them by evidence level from FDA-approved drugs like terzepatide to experimental compounds like BPC-157. He discusses metabolic agents, growth hormone secretagogues, and repair peptides, sharing personal usage experiences and clinical data. The episode emphasizes distinguishing between robust human trials and anecdotal reports while warning against bro science.
Topics discussed
Sponsors and episode introduction
Disclaimer and evidence rating system explanation
Overview of top 11 peptides and selection criteria
Terzepatide: Mechanism, efficacy, and side effects
Retatrutide: Triple agonist potential and risks
Tesamorelin: Visceral fat reduction and GH signaling
Ipamorelin: Selective GH secretagogue benefits
BPC-157: Healing properties and regulatory status
TB-500: Thymosin beta-4 and wound healing
GHK-Copper: Skin health and topical vs systemic use
KPV: Anti-inflammatory peptide for gut and skin
PT-141: FDA-approved treatment for sexual desire
MOTS-c and SS-31: Mitochondrial function peptides
Summary of user reports and final conclusions
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