#583 Don't Get Blood Work Before Listening To This!
Jul 30, 2026 · 1h 0m
Summary
Joe DeFranco shares vacation updates and announces the completion of his "Lean Bastard" program before discussing how strength training affects blood work. He details five blood markers like ALT, AST, CK, creatinine, CRP, and white blood cells. He explains how recent workouts can falsely elevate these markers, causing unnecessary medical concern. DeFranco advises listeners to avoid intense training 48-72 hours before blood draws to ensure accurate results reflect true baseline health.
Topics discussed
Intro: Building a gym brand and Jersey Shore vacation recap
Training on vacation: Routine, soreness, and gym experiences
Launching the Lean Bastard program and recipe guide
Personal transformation: Why the Lean Bastard program works
Main topic: How training affects blood work results
Liver enzymes (ALT/AST): Misdiagnosis due to strength training
PSA levels: Impact of sexual activity on test results
Creatine Kinase (CK): Muscle damage vs. medical concerns
Creatinine and EGFR: Kidney function markers in lifters
C-Reactive Protein (CRP): Inflammation from lifting
White Blood Cells: Stress response to intense workouts
Conclusion: Advice for accurate blood work and disclaimer
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