Essentials: Tools for Hormone Optimization in Males | Dr. Kyle Gillett
Jul 2, 2026 · 40m
Summary
Andrew Huberman interviews Dr. Kyle Gillette on optimizing male hormones through diet, exercise, and lifestyle. They discuss blood work markers like SHBG, the risks of caloric restriction, and supplements such as creatine, Tongkat Ali, and L-carnitine. The episode also covers testosterone therapy protocols, Clomid usage, and topical treatments for hair loss.
Topics discussed
Introduction and the importance of baseline blood work
Dietary pillars: Dairy, IGF-1, and fiber for gut health
Caloric restriction, stress, and finding life purpose
Sponsor: Element electrolyte drink
Exercise protocols for hormonal optimization
Testosterone replacement therapy (TRT) considerations
Creatine supplementation and hair loss myths
Beta-alanine and L-carnitine dosing and benefits
Boron, Vitamin D, and SHBG management
Tongkat Ali and Fadogia agrestis for testosterone
Sponsor: AG1 daily nutritional supplement
Fadogia agrestis safety and dosing protocols
TRT dosing, monitoring, and potential side effects
Clomiphene (Clomid) and SERMs for fertility
Sponsor: David protein bars
Alcohol's impact on hormones and sleep
Tadalafil (Cialis) for blood flow and sleep apnea
Topical DHT blockers for hair loss without side effects
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