Huberman Lab Huberman Lab

Essentials: Tools for Hormone Optimization in Males | Dr. Kyle Gillett

Jul 2, 2026 · 40m

Summary

Andrew Huberman interviews Dr. Kyle Gillette on optimizing male hormones through diet, exercise, and lifestyle. They discuss blood work markers like SHBG, the risks of caloric restriction, and supplements such as creatine, Tongkat Ali, and L-carnitine. The episode also covers testosterone therapy protocols, Clomid usage, and topical treatments for hair loss.

Topics discussed

Introduction and the importance of baseline blood work Dietary pillars: Dairy, IGF-1, and fiber for gut health Caloric restriction, stress, and finding life purpose Sponsor: Element electrolyte drink Exercise protocols for hormonal optimization Testosterone replacement therapy (TRT) considerations Creatine supplementation and hair loss myths Beta-alanine and L-carnitine dosing and benefits Boron, Vitamin D, and SHBG management Tongkat Ali and Fadogia agrestis for testosterone Sponsor: AG1 daily nutritional supplement Fadogia agrestis safety and dosing protocols TRT dosing, monitoring, and potential side effects Clomiphene (Clomid) and SERMs for fertility Sponsor: David protein bars Alcohol's impact on hormones and sleep Tadalafil (Cialis) for blood flow and sleep apnea Topical DHT blockers for hair loss without side effects
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