Huberman Lab Huberman Lab

Essentials: How to Optimize Female Hormone Health for Vitality & Longevity | Dr. Sara Gottfried

Aug 13, 2026 · 38m

Summary

Andrew Huberman interviews Dr. Sarah Gottfried on precision medicine for women, covering hormonal health across decades. They discuss biomarkers, the impact of oral contraceptives, and managing PCOS and insulin resistance. Key topics include stress reduction, microbiome health, and the link between perimenopause, brain metabolism, and Alzheimer’s risk. Dr. Gottfried also emphasizes the importance of coronary artery calcium scoring for early cardiometabolic detection.

Topics discussed

Introduction and intergenerational hormonal health Biomarkers and testing by decade: Teens to 30s Micronutrient testing and vegetable intake Microbiome support and female constipation causes Stress reduction tools and testosterone decline PCOS diagnosis, risks, and continuous glucose monitors Exercise types, cortisol, and personal health journey Oral contraceptives: benefits, risks, and side effects Sleep optimization and preparing for menopause Perimenopause, brain metabolism, and cardiac screening
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