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A KNOCKOUT! (but just audio)

Mar 30, 2026 · 2h 28m

Summary

This bonus episode of "Engineering Disasters with Slides" features guest Ali Maddick, a consultant anesthetist, who explores the history of anesthesia. They discuss pre-anesthetic surgical horrors, including Robert Liston’s fatal amputation, and the development of ether, chloroform, and cocaine as painkillers. The conversation covers the tragic stories of pioneers like Horace Wells and the controversial use of cocaine in early spinal anesthesia.

Topics discussed

Introduction: Engineering Disasters with Slides and Anesthesia Pre-anesthesia history: Speed, pain, and ancient remedies The discovery of ether and nitrous oxide Horace Wells, William Morton, and the race for credit Chloroform, James Simpson, and Victorian anesthesia Muscle relaxants, curare, and regional anesthesia Modern anesthetic machines and safety monitoring Airway management and the Sellick maneuver Gas supply systems and pin indexing safety Disaster case study: The Adam Ackle incident Awareness under anesthesia and patient stories Drug labeling, branding, and pharmaceutical economics Mortality statistics and the safety of modern anesthesia Conclusion: Progress, disasters, and future episodes
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