A KNOCKOUT! (but just audio)
Mar 30, 2026 · 2h 28m
Summary
This bonus episode of "Engineering Disasters with Slides" features guest Ali Maddick, a consultant anesthetist, who explores the history of anesthesia. They discuss pre-anesthetic surgical horrors, including Robert Liston’s fatal amputation, and the development of ether, chloroform, and cocaine as painkillers. The conversation covers the tragic stories of pioneers like Horace Wells and the controversial use of cocaine in early spinal anesthesia.
Topics discussed
Introduction: Engineering Disasters with Slides and Anesthesia
Pre-anesthesia history: Speed, pain, and ancient remedies
The discovery of ether and nitrous oxide
Horace Wells, William Morton, and the race for credit
Chloroform, James Simpson, and Victorian anesthesia
Muscle relaxants, curare, and regional anesthesia
Modern anesthetic machines and safety monitoring
Airway management and the Sellick maneuver
Gas supply systems and pin indexing safety
Disaster case study: The Adam Ackle incident
Awareness under anesthesia and patient stories
Drug labeling, branding, and pharmaceutical economics
Mortality statistics and the safety of modern anesthesia
Conclusion: Progress, disasters, and future episodes
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