Emily McDonald: Can You Rewire Your Brain?
Mar 19, 2026
Summary
Trevor Noah and Eugene Lee speak with neuroscience PhD Em about rewiring the brain to break addictions like vaping by changing dopamine associations. They explore how habits form through cue-response loops and why cold turkey often fails due to stress-induced impulse control loss. Em bridges scientific concepts like neuroplasticity with spiritual practices, explaining how visualization and intuition align with brain function. The discussion also covers the history of science dismissing spiritual ideas and how to critically evaluate research studies.
Topics discussed
Intro: Intergenerational living and sponsor reads
Guest background: Pre-med to neuroscience research
Nicotine addiction and the mechanics of craving
Dopamine, salience, and habit formation
Relapse triggers and the role of stress
Neuroscience of meditation and binaural beats
Sponsors: Apple Card, HelloFresh, and Carhartt
Spirituality, religion, and past life regression
Critique of pop psychology and study validity
Epigenetics and gene expression
Intergenerational care models and sponsors
Neuroplasticity, sensory deprivation, and ADHD
Stress responses and the 'deer in headlights' effect
Visualization techniques and mental rehearsal
Reprogramming the brain for relationships
Self-talk, journaling, and affirmations
Psychedelics, ayahuasca, and addiction recovery
Hypnosis, identity change, and societal structures
Conclusion: Changing internal reality and final sponsors
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