Unexplainable Unexplainable

An Alzheimer's breakthrough?

Oct 19, 2026 · 28m

Summary

Vox senior correspondent Dylan Scott discusses recent breakthroughs in Alzheimer’s research, including new drugs that slow disease progression and a controversial experimental surgery in China that has shown promising results. The episode explores the potential of the shingles vaccine for prevention and addresses the ethical pressures and historical fraud that have plagued the field. Scott explains why these developments offer genuine hope for making Alzheimer’s a treatable condition, despite the need for further validation and replication of the surgical techniques.

Topics discussed

Sponsor: TikTok Sponsor: Bombas Viral videos of Alzheimer's patients recovering in China Introduction to guest Dylan Scott and the episode's focus The dark era of Alzheimer's research and the controversial FDA approval Why Dylan Scott now says to 'believe the hype' about breakthroughs Basic explanation of how Alzheimer's works in the brain Prevention strategies: lifestyle factors and the shingles vaccine link Current treatments: Lecanemab and Donanemab drugs The experimental Chinese surgery: evidence, skepticism, and replication Sponsor: Quince Sponsor: TikTok Sponsor: American Express Why the pressure to cure Alzheimer's leads to fraud and desperation The emotional toll on families and the concept of 'two deaths' Balancing optimism with realism about future progress Outro, credits, and next episode teaser Sponsor: Blinds.com Sponsor: Checkout.com
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