The Journal. The Journal.

The Cancer Vaccine That Could Save Moderna

Aug 28, 2026 · 25m

Summary

The Journal examines Moderna’s pivot from its pandemic-era COVID vaccine success to a promising new cancer treatment. Despite a 90% stock drop and financial struggles, the company’s mRNA melanoma vaccine showed strong results in preventing cancer recurrence. This breakthrough, developed with Merck, signals a major strategic shift toward oncology and offers hope for Moderna’s future viability.

Topics discussed

Moderna's stock crash and surprising cancer vaccine breakthrough Moderna's origins and early hesitation to target cancer Internal debate: Realists vs. Dreamers on oncology Seed funding and partnership with Merck Pandemic pivot, financial boom, and post-COVID slump Promising Phase 2 and 3 trial results for melanoma FDA approval hopes and future of mRNA oncology New 'My Monday Morning' series and show credits
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