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A Flood of New, Deadlier Drugs

May 26, 2026

Summary

NYT reporter Azam Ahmed discusses the rise of ultra-potent synthetic drugs like nitazenes, which are outpacing fentanyl in lethality and ease of production. He details an investigation into Cook County Jail, where inmates smoke drug-soaked paper smuggled in via mail and Amazon, illustrating the failure of supply-side enforcement. Ahmed argues that traditional drug war tactics are ineffective against this adaptive market, advocating instead for harm reduction strategies and treating addiction as a public health crisis rather than a criminal issue.

Topics discussed

Intro: Apple Card ad and episode overview The rise of synthetic drugs and the failure of the war on drugs Nitazenes: A new class of ultra-potent opioids Drug-soaked paper epidemic in Cook County Jail Psychology of use: Desperation, tolerance, and risk Sponsors: IRC, Vital Global, and NY Community Trust Investigation: Tracking the 'paper baron' through a girlfriend The bust, the Hydra effect, and new smuggling methods Solutions: Why enforcement fails and harm reduction works Sponsors: National Park Foundation, E-Trade, and IBM News: Iran strikes, White House shooting, and Pope on AI
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