#534: Supplements in Primary Care
Jul 27, 2026 · 1h 24m
Summary
Hosts Dr. Matthew Frank-Watto and Dr. Paul Nelson-Williams discuss a clinical framework for counseling patients on supplements, emphasizing evidence, mechanism, and risk. They critique popular products like AG1 and multivitamins, noting limited clinical benefit and high costs. The episode also reviews fish oil, highlighting its lack of cardiovascular outcome benefits in trials and a potential link to atrial fibrillation at high doses.
Topics discussed
Introduction and episode overview
Case presentation and supplement inquiry framework
Regulatory landscape and proprietary blends
Sponsors: Figs and Panacea Legal
Multivitamins and AG1 evidence review
Fish oil, omega-3s, and cardiovascular health
Omega-3s and brain health
Magnesium for sleep, constipation, and cramps
Vitamin D and K2 supplementation guidelines
Creatine for muscle and cognitive health
Curcumin and turmeric for inflammation
Summary, resources, and outro
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