The Curbsiders Internal Medicine Podcast The Curbsiders Internal Medicine Podcast

#534: Supplements in Primary Care

Jul 27, 2026 · 1h 24m

Summary

Hosts Dr. Matthew Frank-Watto and Dr. Paul Nelson-Williams discuss a clinical framework for counseling patients on supplements, emphasizing evidence, mechanism, and risk. They critique popular products like AG1 and multivitamins, noting limited clinical benefit and high costs. The episode also reviews fish oil, highlighting its lack of cardiovascular outcome benefits in trials and a potential link to atrial fibrillation at high doses.

Topics discussed

Introduction and episode overview Case presentation and supplement inquiry framework Regulatory landscape and proprietary blends Sponsors: Figs and Panacea Legal Multivitamins and AG1 evidence review Fish oil, omega-3s, and cardiovascular health Omega-3s and brain health Magnesium for sleep, constipation, and cramps Vitamin D and K2 supplementation guidelines Creatine for muscle and cognitive health Curcumin and turmeric for inflammation Summary, resources, and outro
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