REBOOT #518: Cardiology Meets Longevity
Summary
Cardiologist Dr. Greg Katz joins The Curbsiders to discuss cardiovascular risk assessment, emphasizing ApoB and Lp(a) over traditional LDL metrics. The episode critiques standard risk calculators for underestimating danger in young patients and highlights the importance of patient-centered care. Hosts explore primary prevention strategies, metabolic health, and the clinical utility of coronary calcium scoring for personalized treatment plans.
Topics discussed
Introduction and guest bio: Dr. Greg Wirtz
Personal interests and advice on elevating patient care
Case 1: Arthur, 46M with metabolic syndrome and risk factors
Sponsor segments: Babbel and Locums
Lipid panel interpretation: LDL vs ApoB and discordance
Statin therapy, targets, and the limitations of guidelines
Risk calculators vs clinical judgment and Lp(a) basics
Lp(a) as a risk marker and lifestyle factors
Sponsor segments: Mint Mobile and Vinted
Coronary Calcium Score vs CTA: Utility and interpretation
Pharmacologic options: Statins, Ezetimibe, and PCSK9 inhibitors
Patient communication and shared decision-making
Case 2: Young woman with family history and normal BMI
Case 3: Gary, 42M on ketogenic diet with high LDL
Keto diet, saturated fat, and the KETO-CTA study
Key takeaways and closing remarks
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