Stuff You Should Know Stuff You Should Know

The Cancer Episode

Sep 17, 2026 · 51m

Summary

Hosts Josh, Chuck, and Jerry explore cancer as an umbrella term for over 200 diseases driven by uncontrolled cell growth and genetic mutations. They discuss risk factors, staging, and the history of treatments like surgery, radiation, and chemotherapy. The episode highlights modern advancements in immunotherapy, CAR-T cell therapy, and AI-assisted diagnostics, while emphasizing the importance of early detection and supportive language for patients.

Topics discussed

Sponsorships: CeraVe, Eating Interrupted, Lowe's Intro and personal cancer experiences Cancer statistics and genetic vs environmental causes Global cancer rates and leading causes of death Rising colorectal cancer in young adults and screening Survival rates and global access to screening Cell division and how cancer cells differ Genetic mutations, P53, and apoptosis Tumor growth, angiogenesis, and immune evasion Sponsorships: Apple Business, Girardelli, Bombas Types of cancer: Carcinoma, Lymphoma, Leukemia Staging cancer from Stage 0 to Stage 4 Remission vs Cure and language around cancer History of cancer treatment: Surgery and X-rays History of chemotherapy and side effects Sponsorships: Bombas, Zepbound, Nourish & Bloom Why cancer is a modern problem and treatment cycles Modern chemo improvements and surgical recovery Immunotherapy, CAR-T, and gene therapy Precision oncology and AI in diagnosis Future projections, psychoneuroimmunology, and language Screening accessibility and insurance coverage Listener mail: A heartwarming story Sponsorships: Tiami, Amika, Girardelli
Listen ad-free on Castria