NPR’s Shortwave explores the scientific renaissance of psychedelic drugs, tracing their shift from counterculture icons to potential psychiatric treatments. Host Regina Barber and guest John Hamilton discuss how researchers at Imperial College London, including Robin Carhart-Harris and David Nutt, pioneered studies on psilocybin for depression and PTSD. The episode highlights the role of ketamine in opening regulatory doors and details the therapeutic protocols involving music and guided sessions.