Could this nasal spray replace all your vaccines one day?
Summary
NPR’s Shortwave explores Stanford immunologist Bali Pulendran’s research into a universal vaccine that activates the ancient innate immune system. Using a nasal spray with synthetic molecules and antigens, the team achieved broad protection against various pathogens in mice. Pulendran discusses potential applications for seasonal respiratory illnesses and pandemic stopgaps, noting that human trials are approximately three to four years away.
Topics discussed
Intro: Universal vaccine concept and innate immunity
Sponsor: Workday AI platform
The innate immune system: Cinderella and Cookie Monster
Nasal spray components and mouse trial results
Future applications: Seasonal use and pandemic response
Timeline for human trials and safety concerns
Transformative impact of universal vaccines
Outro and credits
Sponsors: Washington Wise, Amazon Health, Capella
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