Short Wave Short Wave

Your DNA is changing all the time. Here’s why

Jun 9, 2026 · 14m

Summary

Host Emily Kwong interviews science journalist Roxanne Comsey about the constant genetic mutations occurring in human cells. They discuss how modern sequencing reveals this internal diversity, linking mutations to health, behavior, and spontaneous corrective events. The conversation also challenges assumptions about parental age, noting that most new mutations in offspring originate from sperm rather than eggs.

Topics discussed

Intro: DNA mutations are constant and diverse Sponsors: NetSuite and Edward Jones Mutations as everyday background noise Environmental factors and behavioral signatures Chance mutations in embryonic development Natural gene therapy and immune system benefits Paternal age and sperm mutation rates Anti-aging therapies and DNA repair challenges Conclusion and credits Sponsors: HomeServe and Tiny Desk Tour
Listen ad-free on Castria