366 | Jim Al-Khalili on Time, Quantum, Biology, and Cosmology
Aug 31, 2026 · 1h 15m
Summary
Sean Carroll interviews physicist Jim Al-Khalili about his new book, *On Time*, exploring the nature of time, entropy, and the arrow of time. They debate whether time’s directionality is fundamental or emergent, discussing the Past Hypothesis and the role of open systems in physics. The conversation also covers quantum mechanics interpretations, the realism of the wave function, and applications in quantum biology, such as proton tunneling in DNA.
Topics discussed
Sponsors: Stamps.com and Wayfair
Introduction: Jim Al-Khalili and the nature of time
Defining time: Tangibility and directionality
Physics vs. Philosophy: The need for interdisciplinary dialogue
Research collaboration and the arrow of time debate
Loschmidt's paradox and open vs. isolated systems
The Past Hypothesis and initial conditions of the universe
Sponsors: Vela and PetSmart
Entropy, gravity, and the role of life in thermodynamics
Quantum interpretations and the origins of quantum biology
Decoherence, entanglement, and quantum effects in nature
Quantum arrows of time and entanglement entropy
Emeritus life and the reality of time
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