Science Vs Science Vs

Fiber Maxxing and Poo Maxxing, with Dr. Trisha Pasricha

Oct 15, 2026 · 59m

Summary

Host Wendy Zuckerman interviews Dr. Trisha Pasricha, a neurogastroenterologist and author of *You’ve Been Pooping All Wrong*, to demystify gut health. They discuss the gut-brain connection, how stress impacts digestion, and the link between constipation and Parkinson’s disease. The episode also covers practical advice on fiber intake, the importance of responding to bowel urges, and why prolonged toilet time can lead to hemorrhoids.

Topics discussed

The rectum spasm: Understanding the urge to go Intro: Gut issues and the 'poop-phoria' concept Guest intro: Dr. Trisha Pasricha and her background Sponsor: Gatorlite hydration Defining 'poop-phoria' and its impact on daily life Growing up in a 'poo-forward' household The origin story: Spies, heart rates, and the gut High school study: Measuring the 'cannonball' feeling The science of nervousness: Amygdala and colon speed Personal anecdote: Stage fright and the 1940s soldier Historical evidence: Psychological stress and gut spasms The vagus nerve: Communication between gut and brain Parkinson's disease: Starting in the gut, not the brain Risk factors: Constipation, exercise, and Parkinson's Fecal transplants: Treating C. diff and peanut allergies The complexity of FMT for neurodegenerative diseases Sponsor: Indeed Sponsored Jobs Sponsor: Checkout.com What is poop? Composition and microbial content Why is poop brown? The role of bile Silver poop: A rare medical emergency Normal frequency: Comfort vs. daily habits The importance of fiber diversity for gut health The 5-minute rule and responding to the urge Why holding it in leads to straining and discomfort Sphincter function and distinguishing gas from solid Hemorrhoids: Anatomy and causes of engorgement Smartphone use in the bathroom and its risks Time limits: Reducing hemorrhoid risk The 'parasite' myth and social media misinformation Gender differences: Why women have higher IBS risk IBS mechanisms: Estrogen, pain signaling, and gas Neuroplasticity and pain perception in IBS Juice cleanses: The problem of removing fiber Evolutionary perspective: Microbes and social bonding Unusual cases: Foreign objects in the rectum Public toilets: To paper or not to paper Closing remarks and recommendations Outro: Link to related episode Sponsor: Oracle AI Database
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