Science Friday host Flora Lichtman interviews Tahir Amin, author of *Pharma Monopoly*, about how the US patent system drives high drug prices. Amin explains that pharmaceutical companies use overlapping patents on formulations and indications to extend monopolies and block generics, citing examples like Keytruda and Humira. He argues that the industry prioritizes shareholder wealth over public health, neglecting unprofitable diseases, and calls for policy reforms such as limiting exclusivity and establishing public manufacturing alternatives.