Science Friday Science Friday

Your DNA is constantly mutating, and that’s a good thing

Apr 27, 2026 · 17m

Summary

Science Friday host Ira Flatow interviews Roxanne Kamsley, author of "Beyond Inheritance," about how DNA mutates throughout life rather than remaining static. They discuss how these spontaneous mutations influence immune function, aging, and diseases like heart disease, while also noting that some mutations can correct inherited disorders. The episode highlights new insights from single-cell sequencing and challenges the stigma surrounding genetic changes.

Topics discussed

Sponsors and show introduction Introduction to Roxanne Kamsey and dynamic DNA The mosaic of genetic diversity in the body Inherited vs. spontaneous mutations and epigenetics Mutations in blood cells and cardiovascular disease Immune system mutations and vaccine mechanics Cancer as a hotbed of genetic mutations Commercial break Beneficial mutations that correct genetic disorders DNA mutations, aging, and longevity research Single-cell sequencing and future treatments Changing perspectives on genetic disease and credits
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