Your DNA is constantly mutating, and that’s a good thing
Apr 27, 2026 · 17m
Summary
Science Friday host Ira Flatow interviews Roxanne Kamsley, author of "Beyond Inheritance," about how DNA mutates throughout life rather than remaining static. They discuss how these spontaneous mutations influence immune function, aging, and diseases like heart disease, while also noting that some mutations can correct inherited disorders. The episode highlights new insights from single-cell sequencing and challenges the stigma surrounding genetic changes.
Topics discussed
Sponsors and show introduction
Introduction to Roxanne Kamsey and dynamic DNA
The mosaic of genetic diversity in the body
Inherited vs. spontaneous mutations and epigenetics
Mutations in blood cells and cardiovascular disease
Immune system mutations and vaccine mechanics
Cancer as a hotbed of genetic mutations
Commercial break
Beneficial mutations that correct genetic disorders
DNA mutations, aging, and longevity research
Single-cell sequencing and future treatments
Changing perspectives on genetic disease and credits
Listen ad-free on Castria