Science Friday Science Friday

Are new treatments for celiac disease on the horizon?

Sep 25, 2026 · 11m

Summary

Dr. Maureen Leonard discusses celiac disease, explaining its immune-mediated nature and the mystery of its unpredictable onset. She highlights promising new therapies, including the drug TEV-408, which aims to block inflammation and protect the intestine from gluten damage. Leonard also shares insights from a long-term birth cohort study tracking environmental and microbiome factors that may trigger the disease in at-risk children.

Topics discussed

Sponsor: Audible Theater's 'A Ghost in Your Ear' Sponsor: NYU Scarball's 'Tom at the Farm' Sponsor: Progressive Insurance Intro: Celiac disease overview and guest introduction Explaining the mechanism of celiac disease Why celiac disease triggers at different times in life New drug TEV-408 and its clinical trial results Other potential treatments in the pipeline Birth cohort study to identify early celiac markers Timeline for new treatments and diagnosis importance Testing recommendations for family members Discussion on historical wheat varieties and gluten intake Closing remarks and guest credits Sponsor: Brooklyn SolarWorks Sponsor: NYC Campaign Finance Board
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