Ray William Johnson recounts five true crime stories involving women who murdered their husbands or partners for financial gain or to escape relationships. The episodes cover Amy, who poisoned her husband after embezzling millions; Shara, who hired a hitman to kill her retired NBA husband for life insurance; Wendy, who murdered her terminally ill husband to secure a lawsuit settlement; Kulsum, an Iranian serial killer who poisoned 13 husbands; and Devin, who shot her ex-boyfriend during a mail route.