Radiolab Radiolab

The Sweetest Thing

Sep 18, 2026 · 31m

Summary

Latif Nasser investigates the science of sweetness after his children ask what the sweetest thing is. He explores how artificial sweeteners, sensory cues like color and sound, and brain lasers can alter perception, revealing that sugar might actually be the most intense natural sweet. The episode concludes with the discovery of a sugar molecule in deep space, suggesting the universe itself might taste like raspberries.

Topics discussed

Sponsor: AT&T iPhone 18 Pro Promo: Radiolab Fanny Pack and The Lab Membership Intro: The quest for the sweetest thing Scientific ranking of sweeteners by potency Tasting experiment: Why potency doesn't equal taste Potency vs. Intensity: Why sugar might be the winner Evolutionary biology: Sweetness as a survival cue Sponsors: Capital One and Smalls Cat Food Promo: This American Life Fruit chemistry: Volatiles and smell enhancing sweetness Visual cues: How color and appearance affect taste Sonic seasoning: The effect of sound on sweetness Neuroscience: Mapping the sweet pathway in the brain Optogenetics: Using lasers to create artificial sweetness Astrobiology: Finding sugar molecules in space Conclusion and credits Update: Latif Nasser's vocal cord injury Staff credits and funding acknowledgments
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