NPR News Now covers the White House's appointment of Stephen Miller as chief of staff following a significant Democratic midterm victory, alongside Republican Jeff Hurd's re-election in Colorado. The broadcast also reports on Scott Wagoner's potential historic win in Mississippi and major tech companies challenging a new California law aimed at protecting children from addictive social media features. Additionally, the episode highlights archaeological evidence of ancient cannabis use in Siberia and NASA's call for new astronaut applicants to support the Artemis program.