This episode explores the historical use of perfumes and scents to combat the plague from the late Middle Ages through the Renaissance. The host discusses how the "plague doctor" logo connects to ancient beliefs that bad odors caused disease, leading to the use of aromatic substances like cinnamon, cloves, and vinegar to purify the air. The discussion covers the Hippocratic theory of humors, which dictated seasonal choices for fumigations and protective sachets, and highlights how these remedies varied based on wealth and gender.