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Why your immune system ages at 40 and 60

Nov 9, 2026 · 4m

Summary

Professor Roseanne Kenny discusses new research indicating that immune system efficiency declines at specific inflection points around ages 40 and 60, rather than linearly. She explains that while the exact causes are unclear, these periods of vulnerability can be mitigated through lifestyle changes and targeted vaccinations. Kenny specifically recommends flu, shingles, and RSV vaccines to support T cell function and reduce the risk of severe viral and bacterial infections during these critical decades.

Topics discussed

Sponsor: Rubrik security and AI operations Intro: Immune system aging research with Prof. Kenny Identifying inflection points at ages 40 and 60 Study methodology: cross-sectional data analysis Lifestyle factors: diet, sleep, and exercise Vaccination strategies for T-cell support RSV vaccination for older adults
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