Cold and Room-Temperature Platelets in Cardiac Surgery, Arginine Therapy for Sickle Cell Disease Acute Pain Episodes, Medications for Alcohol Use Disorder, and more
Summary
JAMA Deputy Editors Linda Brubaker and Preeti Malani discuss recent research, including a trial showing cold-stored platelets are non-inferior for cardiac surgery bleeding control. They cover negative results for IV arginine in sickle cell pain crises but highlight zinc’s potential to reduce infections in young children with the disease. The episode also addresses emergency department boarding delays, rising malaria resistance in Ethiopia, AI’s role in medicine, and underused treatments for alcohol use disorder.
Topics discussed
Introduction and episode overview
Cold-stored platelets in cardiac surgery
IV arginine for sickle cell pain crisis
Zinc supplements to prevent infections in sickle cell
Emergency department boarding delays
Rising malaria resistance in Ethiopia
AI in medicine and HIV exclusion in gene therapy
Medications for alcohol use disorders
Alcohol-related liver disease and closing remarks
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