Hidden Brain Hidden Brain

How to Combat Pain

Jul 20, 2026 · 50m

Summary

Host Shankar Vedantam interviews pain psychologist Rachel Zofnes, who challenges the biomedical model by explaining that pain is constructed by the brain as a danger alarm. Zofnes illustrates how context, emotions, and social factors influence pain through stories of phantom limb sufferers and patients responding to placebos. She advocates for a biopsychosocial approach, showing how addressing sleep, diet, and mental health can effectively reduce chronic pain.

Topics discussed

Introduction: The mystery of pain and its true nature Sponsor messages: CuriosityStream, LinkedIn, and Progressive The biomedical model vs. the brain as a danger detector Case study: The construction worker with the nail in his boot Case study: The nail gun accident and lack of pain Why context and perception dictate pain intensity Sponsor messages: Sprouts and The Big Bang Theory Phantom limb pain and the brain's body map Case study: Mateo's amputation and phantom pain How context and emotions influence pain experience Sponsor messages: SNHU and BetterHelp The biopsychosocial model of pain The impact of social connection and isolation on pain High pain vs. low pain recipes and detective questions Case study: Kai's placebo gummy bears and pain relief Case study: Sam's recovery through lifestyle changes Conclusion, credits, and final sponsor messages
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