Hidden Brain Hidden Brain

Stepping Out of the Shadows

Jun 22, 2026 · 1h 28m

Summary

Host Shankar Vedantam interviews psychologist Alison Ledgerwood about the brain’s evolutionary negativity bias, which causes us to fixate on threats and mistakes. They explore how this bias influences memory, decision-making, and geopolitical conflicts through framing effects. Ledgerwood offers strategies to rebalance this tendency, such as practicing gratitude, sharing positive experiences, and using humor to interrupt negative spirals.

Topics discussed

Introduction: The evolutionary design of the brain Sponsor messages: TikTok, LinkedIn, and Progressive The negativity bias in daily life and work Case study: NASA's Genesis mission failure Negativity bias in geopolitics and war Sponsor messages: Sprouts and HBO Max Evolutionary roots: Why we focus on threats Neuroscience of negativity and framing effects Classic study: Disease outbreak framing Asymmetric impact of negative vs positive frames Sponsor messages and listener feedback intro Strategies to counter negativity: Gratitude and sharing Reframing mistakes and the psychology of disgust Sponsor messages: Sprouts and HBO Max Listener questions on disgust sensitivity and trypophobia Sponsor messages: LinkedIn and BetterHelp Social and cultural dimensions of disgust Sponsor messages and transition to listener stories Managing disgust in healthcare and public health Conclusion and final sponsor messages
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