Hasan Minhaj Doesn't Know Hasan Minhaj Doesn't Know

The Next (And Final) Pandemic? with Annie Jacobsen

Aug 19, 2026 · 1h 11m

Summary

Hasan Minhaj interviews author Annie Jacobson about her book *Biological War: A Scenario*, exploring the existential threat of bioweapons and lab leaks. They discuss the history of US and Soviet biological warfare programs, the dangers of gain-of-function research, and the low barrier to entry for creating pathogens using AI. The episode highlights the vulnerability of global public health infrastructure and the potential for engineered diseases to cause rapid societal collapse.

Topics discussed

Intro: Current events and public health infrastructure concerns History of US biological weapons programs and field trials Soviet bioweapons, the Biological Weapons Treaty, and lab safety Gain of function research and its controversial risks Lab accidents, explosions, and the threat of bioweapons Interview with Annie Jacobson on her new book 'Biological War' Differences between nuclear and biological warfare scenarios Lab safety levels (BSL-3/4) and pathogen definitions Lab leaks, cover-ups, and theft of biological agents Virulence, transmissibility, and medical countermeasures Chimera pathogens and genetic engineering accessibility AI in bioweapons and global biological weapons programs Expert opinions on gain of function and pneumonic plague symptoms Euphoria genes and the Strategic National Stockpile location AI data leaks, volunteer responders, and the Insurrection Act The Devolution Plan and government continuity protocols Apocalypse ASMR: A grim scenario of plague outbreak
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