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#112 How To Slow Biological Aging With a Multivitamin, Vegetables, & Omega-3 | Dr. Steve Horvath

Jun 7, 2026 · 2h 47m

Summary

Host Rhonda Patrick interviews Dr. Steve Horvath, pioneer of epigenetic clocks, to discuss how DNA methylation measures biological aging. They explore different clocks like GrimAge and Dunedin Pace, clarifying that they track distinct aspects such as mortality risk and aging pace rather than a single number. The conversation covers whether lifestyle changes, supplements, and medical interventions like GLP-1 drugs or metformin can reverse epigenetic age. Horvath emphasizes that while some interventions show modest reversals, claims of dramatic rejuvenation are often overstated.

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