Host Rhonda Patrick interviews Dr. Charles Brenner, discoverer of nicotinamide riboside, to explore NAD biology and its role in cellular energy and inflammation. They discuss how chronic conditions like obesity and sleep deprivation tax NAD levels, while NR supplementation offers anti-inflammatory benefits and aids exercise recovery. The episode also covers emerging data on NR’s potential to improve fertility, maternal lactation, and offspring development, alongside practical advice on supplement timing and the limitations of blood NAD testing.
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