Dr. Rangan Chatterjee interviews exercise physiologist Dr. Stacey Sims about why conventional fitness advice often fails women in midlife. They discuss how perimenopause alters physiology, making resistance training and HIIT essential for maintaining strength, bone density, and metabolic health, rather than just walking. Dr. Sims explains that estrogen loss impacts muscle contraction and gut health, requiring specific adaptations to prevent visceral fat gain and cognitive decline. The episode offers practical tips for time-pressed women to incorporate heavy lifting and high-intensity interv…