Host Thomas Goetz explores the history of ivermectin, from its discovery as a Nobel Prize-winning treatment for parasitic diseases like river blindness to its controversial misuse during the COVID-19 pandemic. The episode contrasts rigorous scientific evidence showing no efficacy against viruses or cancer with the rise of anecdotal claims and political movements promoting unproven uses. It examines how misinformation eroded public trust in medical institutions and highlights the ongoing tension between scientific validation and "medical freedom."