49ers Talk: A San Francisco 49ers Podcast 49ers Talk: A San Francisco 49ers Podcast

49ers welcome reinforcements as CJ West joins growing injured list

Sep 24, 2026 · 41m

Summary

The 49ers face a critical roster crisis with 15 players on injured reserve, the highest in the NFC West, forcing difficult decisions on return eligibility. Hosts discuss the addition of veteran wide receiver Brandon Cooks to the practice squad and the signing of defensive lineman Niko Jones to address depth issues. The episode also highlights Brock Purdy’s historic performance against Miami, noting his consistency and elite decision-making, while analyzing the team’s defensive struggles and upcoming matchup against the Arizona Cardinals.

Topics discussed

Big O Tires and Ozempic advertisements ZocDoc ad and 49ers 2-0 record intro Roster update and veteran receiver addition Injury report and IR return limits analysis League-wide injury trends and 49ers comparison Key injury areas: WR and Defensive Line Brandon Cooks practice squad elevation potential Determining the third starting wide receiver Playbook integration for new receivers Brandon Cooks age, speed, and consistency Toyota and UBS Financial advertisements Brock Purdy performance and MVP discussion Purdy's historic stat line and consistency Purdy's coachability and decision making Fred Warner's perspective on Purdy's growth Purdy's consistency since first NFL start Purdy's confidence and resilience in bad games Offensive line protection and Purdy's confidence Criticism of Purdy and defensive line depth Amica Insurance and Shopify advertisements Run defense stats and offensive line struggles Defensive line rotation and practice squad calls Orlo Height injury and defensive line outlook Cardinals game preview and run game focus Cardinals roster and quarterback situation Cardinals injury outlook and receiving core Brandon Cooks background and episode wrap-up Zepbound medication advertisement
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